Biostimulators
Treatment Time
30–60 minutes
Numbing
Optional
Discomfort
Minimal
Recovery Time
1–3 days

Treatment Overview
At The Face Institute, Biostimulators like Sculptra® and Radiesse® offer a non-surgical way to restore volume, smooth fine lines, and improve skin texture by stimulating the body’s natural collagen production. Unlike traditional fillers that add immediate volume, biostimulators work gradually to enhance skin structure and firmness over time, providing long-lasting and natural-looking results.
Sculptra® is a poly-L-lactic acid (PLLA) based biostimulator that improves skin laxity and restores lost facial volume, while Radiesse® is a calcium hydroxylapatite (CaHA) based biostimulator that provides immediate volume with long-term collagen stimulation. Both treatments are ideal for those looking to enhance facial contours, correct volume loss, and achieve a more youthful, refreshed appearance without an overfilled look.
Book your complimentary consultation at The Face Institute and experience the power of collagen-stimulating biostimulators.
How to Prepare
Follow these preparation steps for optimal results:
Consultation: Meet with our expert injectors to assess your skin, discuss your goals, and determine whether Sculptra® or Radiesse® is the best option for you.
Avoid Blood Thinners: Refrain from taking aspirin, ibuprofen, or other NSAIDs at least a week before your treatment to minimize bruising. Always consult your doctor before stopping prescribed medications.
Stay Hydrated: Drinking plenty of water before and after treatment helps support the collagen-building process.
Limit Alcohol & Caffeine: Reduce alcohol and caffeine intake for at least 24 hours before treatment to decrease the risk of swelling.
What to Expect
We ensure a comfortable and personalized treatment experience:
Step 1 – Facial Assessment & Mapping: Our expert injector will evaluate your facial structure and create a customized injection plan based on your unique needs.
Step 2 – Precise Injection Process:
- Sculptra® is injected both deep and superficially across the entire face, followed by gentle massaging to stimulate gradual collagen production over time.
- Radiesse provides immediate volume, similar to HA fillers, but works as a scaffold to encourage natural collagen growth which improves over time.
Step 3 – Natural Rejuvenation Begins: Over the following weeks and months, your skin naturally regenerates collagen, leading to gradual volume restoration and improved skin texture.
Minimal Downtime: Most patients experience only mild swelling or tenderness, which resolves within a few days.
Aftercare
To maximize your results and ensure smooth recovery, follow these aftercare tips:
Massage the Treated Area: For Sculptra®, gently massage the treated areas for 5 minutes, 5 times a day, for 5 days to ensure even distribution.
Radiesse® treatment does not require massage. Applying ice can aid in post-treatment healing, with full results visible within two weeks.
Avoid Strenuous Activity: Refrain from intense exercise, excessive heat, and sun exposure for 24–48 hours after treatment.
Stay Hydrated: Drink plenty of water to support collagen production and skin hydration.
Limit Alcohol & Caffeine: Avoid alcohol for 24 hours post-treatment to reduce swelling.
Want to know more? Send us a message
The benefits of
Biostimulators
Restore lost volume and stimulate collagen naturally with Sculptra® & Radiesse® at The Face Institute in Edmonton. Achieve long-lasting facial rejuvenation. Book your consultation today!
Stimulates natural collagen production for long-lasting volume restoration
Improves skin elasticity, firmness, and texture
Provides subtle, natural-looking enhancement without an overfilled appearance
Long-lasting results that develop gradually over several months
Non-surgical and minimally invasive with minimal downtime
Before & After
Frequently Asked Questions
What are Sculptra® and Radiesse® biostimulators?
Sculptra® and Radiesse® are injectable treatments designed to stimulate collagen production and gradually restore lost volume in the face, hands, and other areas of the body. Unlike traditional fillers, these treatments work over time to strengthen skin structure and improve skin texture. Sculptra® contains poly-L-lactic acid, which rebuilds collagen deep within the skin, while Radiesse® contains calcium hydroxylapatite microspheres that both fill and stimulate collagen.
They’re great for softening smile lines, marionette lines, and volume loss in the cheeks or jawline. Both options provide a refreshed and youthful look without the “overfilled” appearance. Patients love the subtle, natural progression of results. These treatments are often chosen for their ability to enhance the skin’s quality, not just volume. Over time, skin looks firmer, smoother, and more resilient.
How long do the results last?
Results from biostimulators develop gradually and typically last between 1.5 to 2 years. Regular maintenance treatments help prolong results. The collagen built during this time stays even after the initial product is absorbed by your body. This means the improvements are more sustainable than traditional fillers.
You may start to notice visible changes by 4–6 weeks post-treatment, with full results in a few months. Many clients opt for touch-ups yearly to maintain peak skin quality. The exact longevity depends on age, skin condition, and lifestyle. Avoiding smoking and excessive sun exposure can also help extend results.
Is the treatment safe?
Yes, both Sculptra® and Radiesse® are FDA and Health Canada-approved and are considered safe when administered by trained professionals. Side effects are minimal and may include mild swelling, redness, or bruising at the injection sites. Because these injectables stimulate your body’s own collagen, they offer a more natural regeneration process. They do not contain animal-based ingredients, making them safe for most patients.
All treatments are preceded by a thorough consultation and safety assessment. Post-treatment, you’ll be advised on gentle massage techniques and aftercare. In rare cases, small nodules may form, which typically resolve on their own. Choosing a skilled provider significantly reduces any risks.
Can I combine biostimulators with other treatments?
Absolutely! Sculptra® and Radiesse® can be paired with dermal fillers, microneedling, PRP, or laser treatments for a comprehensive approach to facial rejuvenation. Our experts will customize a treatment plan tailored to your aesthetic goals. Combination therapy targets both volume and surface concerns, like fine lines or texture. Microneedling and PRP can amplify collagen stimulation and improve skin tone.
Laser treatments can address pigmentation and firmness alongside volume restoration. Timing your treatments correctly ensures the safest and most effective results. We’ll create a timeline that fits your lifestyle, downtime needs, and budget. Many clients achieve transformational, yet natural-looking changes with this approach.
When will I see results?
Results appear gradually over a few months as the body produces new collagen. Radiesse® provides some immediate volume, while Sculptra® works more slowly but delivers longer-lasting improvements. Initial plumpness with Radiesse® is often visible right after the appointment. Sculptra® encourages your body to rebuild lost structure over 2–3 months. The gradual onset ensures subtle changes, avoiding dramatic shifts.
You’ll notice firmer, lifted skin and an overall refreshed appearance. Full results typically peak around 3–6 months, depending on your treatment plan. This slow build-up means you’re less likely to look “done” and more likely to hear, “You look so well-rested!”
Are there any side effects?
Mild redness, swelling, or tenderness may occur but typically resolves within a few days. Following post-care instructions will help minimize any temporary effects. Bruising is also possible but can be covered with makeup after 24 hours. We advise clients to avoid strenuous exercise, saunas, and alcohol post-treatment.
Massage is often recommended after Sculptra® to ensure even product distribution. All side effects are short-term and rarely interfere with daily routines. You’ll be given specific care instructions tailored to your skin and procedure. Any unusual reactions are very rare but will be addressed promptly by our team.
Who is a good candidate for Sculptra® and Radiesse®?
This treatment is ideal for individuals 30 years plus looking to restore facial volume, improve skin elasticity, and achieve natural-looking rejuvenation. It is perfect for those seeking gradual, long-term enhancement rather than immediate but temporary results. It’s a great option for people noticing early signs of aging or skin thinning.
Candidates often include those who want to avoid invasive surgery or “overfilled” results. Sculptra® is particularly well-suited for full-face rejuvenation, while Radiesse® is excellent for hands, cheeks, and jawlines. These injectables can also help balance facial asymmetry or enhance contour. A consultation will determine if biostimulators match your skin goals. Patients with active infections, autoimmune conditions, or certain allergies may not be eligible.
What areas can be treated with biostimulators like Sculptra® and Radiesse®?
Sculptra® and Radiesse® are versatile and can treat multiple areas of the face and body. Common treatment zones include the cheeks, temples, jawline, and nasolabial folds. Radiesse® is also FDA-approved for hand rejuvenation, restoring volume and hiding veins. These products are increasingly used for off-face areas like the neck, décolleté, and even upper arms.
Sculptra® can help reduce cellulite or crepey skin in the thighs and buttocks. Both are excellent for improving skin laxity and volume where it’s been lost due to aging. Treating multiple areas allows for a more balanced, harmonious result. Your injector will guide you on the best use based on your anatomy and goals.

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